"Born Again" tells the story of 2 men and 1 woman who become involved in the 1980's and again in the present day through reincarnation and fate.
In the 1980's, Kong Ji Cheol denies his fate to become devilish like his father. In the present day, Cheon Jong Beom is a medical school student.
In the 1980's, Jung Ha Eun suffers from dilated cardiomyopathy. She owns the used bookstore "Old Future." In the present day, Jung Sa Bin is an instructor of archaeology. She pets nameless remains warmly and figures out their story. The secret of those nameless remains are uncovered.
In in the 1980's, Cha Hyeong Bin is a detective who loves only one person. In the present day, Kim Soo Hyeok is a prosecutor, who believes in a crime gene that is inherited.